Mechanism of Action: Letrozole is a aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This can slow or stop the growth of some breast cancers that need oestrogen to grow. In addition, it is also useful in infertility whereby it increases the release of certain hormones to stimulate the release of eggs from the ovaries.

Indications:

• In the treatment of infertility due to anovulation

Dosage: Total dosage administration is generally limited to 5 days at 2.5 to 7.5mg daily,