Mechanism of Action: Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve sreband rejuvenates damaged nerve cells.
Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain.